Malignant fibrous histiocytoma 20 i fig 2 cat 1neoplastic multinucleated giant cells and fibroblasts he fig 3 dog 1mixture of cells storiform pattern and lobulationhe fibrous histiocytoma giant cell variety upon review of this group of cases. Malignant fibrous histiocytoma in dogs and cats gleiser ca raulston gl jardine jh gray kn five soft tissue tumors of varied morphology in dogs and cats were classified as malignant fibrous histiocytomas on the basis of their histologic composition. A malignant fibrous histiocytoma refers to an invasive tumor that contains an excessive number of histiocytes the white blood cells that reside within the normal connective tissue of the body referred to as tissue macrophages histiocytes play a defensive role in the bodys immune response engulfing cellular debris and infectious agents as well as initiating defense mechanisms in the system. In addition if it is malignant a little area around the growth will be gotten rid of along with the growth itself to guarantee all the cancer has been removed the larger and uncommon fibrous histiocytomas will have to be surgically gotten rid of with the animal under sedation and stitches may be required recovery of histiocytoma in dogs. Research in veterinary science 1992 53 198 204 malignant fibrous histiocytomas in dogs and cats an immunohistochemical study r j m m thoolen j h vos j s van der linde sipman r a de weger j a m van unnik w misdorp j e van dijk department of veterinary pathology branch laboratory animal pathology and special animal diseases faculty of veterinary medicine
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